学术报告

题目: Label-free Optical Micro Imaging towards Tissue Histologyin vivo

报告人: Xingde Li, PhD (Professor of Department of Biomedical Engineering,Department of Electrical and Computer Engineering,Johns Hopkins University,Baltimore, MD 21205)

摘要:This talk reports on our recent development of high-resolution, nonionizing biophotonic imaging technologies, including optical coherence tomography (OCT) and multiphoton endomicros- copy. These fiber-optically based technologies have shown significant translational potential for imaging tissue microanatomiesin vivoat a resolution approaching or at that of standard histopathology but without the need for tissue removal or staining. The physics principles, engineering challenges and (big) data and image processing challenges, and potential solutions will be briefly discussed, including the development of advanced lasers, MEMS technology, custom optical fiber, ultracompact and high-performance micro optics, speckle noise reduction, image segmentation and optical staining techniques. Representative applications of these high-resolution technologies will be presented, including cancer detection, airway physiology assessment, preterm birth risk assessment, and intra-operative guidance for neurosurgery. Other potential applications towards basic research such as functional neuroimaging on awake animals will also be discussed.

时间: 6月30日(周二) 9:50

地点: 致远楼102

欢迎参加！

数学系

SHORT BIOSKETCH

Dr. Xingde Li received his PhD degree in Physics from the University of Pennsylvania in 1998. He is currently a professor at the Department of Biomedical Engineering Johns Hopkins University with a joint appointment with the Department of Electrical and Computer Engineering. His research interest focuses on development of noninvasive and transformative optical micro imaging technologies for early disease diagnosis and interventional guidance. He has published about 90 peer-reviewed journal papers, with a total citation >10,300 and an H-index~43 (according to Google Scholar). He served as the chair for the Emerging technologies Committee of the IEEE-EMBS society (2006 – 2010). He has also been chairing many conferences such as the recent OSA Biomedical Optics Topical Meetings 2010-2014 etc. He currently serves on the editorial board of several international journals in the area of biomedical photonics includingthe Journal of Biomedical Optics(SPIE),Biomedical Optics Express(OSA),the IEEE Transactions on Biomedical Engineering,Light: Science and Applications(Nature Publishing Group and CIOMP). He is a Fellow of OSA, SPIE, and AIMBE.

Website: http://www.bme.jhu.edu/people/primary.php?id=915