题目:The Nested Method and Immuno-epidemiological Models
时间:5月23日(星期一),上午 9:00-10:00
李学志教授,安阳工学院副校长,北京信息与控制研究所博士生导师,河南省优秀专家,河南省劳动模范、河南省学术与技术带头人,中国生物数学会常务理事,《应用泛函分析学报》、《国际数学建模、模拟与应用》杂志编委,《国际生物数学与系统生物学》杂志副主编,美国《数学评论》评论员,国家自然科学基金同行评审专家。主要研究方向:泛函分析及应用;生物数学;传染病动力学。主持国家自然科学基金面上项目4项,主持国家自然科学基金对外合作与交流项目4项,主持河南省杰出青年科学基金项目、河南省科技创新杰出人才支持计划项目等省部级项目12项。出版学术著作5部,在国外和国内核心期刊发表学术论文130余篇,其中被SCI收录70余篇,培养已毕业博士研究生5人,已培养硕士研究生48人,12次应邀到美国、意大利、加拿大、日本、韩国、印度等国访问、讲学,37次应邀在全国或国际学术会议上作学术报告。
The results in the field of Mathematical modeling and researches in within-host virus infection systems (micro) and diseases transmission systems among hosts (Macro) are very plentiful. Since it has very closed relations between the virus munber within a host and the ability of disease transmission of this host, it is of great significance and realistic meaning to formulate and to investigate coupled systems between immunological and epidemiological systems to reveal the mechanism of disease transmission. In this talk, what is the nested method and how to use this mehtod to formulate the immuno-epidemiological models, are introduced. A two-strain immuno-epidemiological model of HIV with superinfection is formulated. The dynamical behavior of this model is analyized. How the with-host parameters affect the HIV transmission are also investigated by numerical simulations.