题目：Multiscale Modeling of Early Mammalian Blastocyst

报告人：杜慧静 博士 (University of Nebraska- Lincoln)

时间：2017年5月19日下午4点

地点：致远楼107室

摘要：

Mathematical biologists apply mathematical, computational and experimental techniques to investigate biological processes at all levels, from the molecular to the population. To setup an approach spanning multiple levels of biophysical reality, I will describe a new 3D hybrid framework which includes three major submodels: the discrete stochastic Subcellular Element Model for individual cellular activity; continuum reaction-diffusion-advection partial differential equations of extracellular biomolecules; a stochastic decision-making model for cell lineage transition. Our results demonstrate how a modeling approach coupling biologically relevant scales can provide new insights into the early embryonic development and other complex biological problems.

欢迎各位参加！